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What is the safest antidepressant while breastfeeding?

Understanding Antidepressant Safety During Breastfeeding
The intersection of mental health treatment and breastfeeding presents a complex challenge for new mothers. While managing postpartum depression is crucial for the well-being of both mother and child, the safety of antidepressants during breastfeeding is a significant concern. Research indicates that all antidepressants do pass into breast milk to some degree, raising questions about their potential effects on nursing infants.
The Leading Contenders: Sertraline and Paroxetine
Among the various options available, sertraline (commonly known by its brand name Zoloft) and paroxetine (Paxil) are frequently highlighted as the safest antidepressants for breastfeeding mothers. These medications have been extensively studied, and evidence suggests they have a favorable safety profile when it comes to breastfeeding. Sertraline, in particular, is often recommended due to its low levels in breast milk and minimal side effects reported in infants.
Clinical guidelines typically suggest that if a mother has previously been treated successfully with a specific antidepressant, it may be beneficial to continue that medication during breastfeeding. This approach not only supports the mother’s mental health but also enhances the likelihood of treatment success.
The Role of Psychotherapy
While pharmacological treatment is essential for many, healthcare providers often recommend starting with psychotherapy as a first-line treatment for postpartum depression. This is particularly relevant for mothers who may be hesitant about medication due to concerns about their infant’s safety. However, when medication is necessary, sertraline and paroxetine are the preferred choices, with other options like citalopram and escitalopram also being considered.
Balancing Risks and Benefits
The overarching consensus among experts is that the benefits of treating maternal depression generally outweigh the potential risks associated with antidepressant use during breastfeeding. Mothers are encouraged to discuss their specific situations with healthcare providers to make informed decisions that prioritize both their mental health and the safety of their infants.
In conclusion, while the decision to use antidepressants during breastfeeding should be made with caution and professional guidance, sertraline and paroxetine stand out as the safest options based on current evidence. This careful balancing act is essential for ensuring the health and happiness of both mother and child during this critical period.

Is Lexapro or Zoloft better for anxiety?

SSRIs like Lexapro and Zoloft make more serotonin available in your brain—which in turn helps to relieve symptoms.. Some research suggests that Lexapro might be slightly more effective than Zoloft in treating depression and anxiety because it works slightly differently from other SSRIs.

Is Prozac better than Zoloft for breastfeeding?

Depressed mothers, in part, do not breastfeed because of their concern about potentially negative effects of antidepressants on their infants. Although sertraline (Zoloft) and paroxetine (Paxol) concentrations are not detectable in infants’ sera, fluoxetine (Prozac) and citalopram (Celexa) do have detectable levels.

What is the safest anxiety medication while breastfeeding?

Safe medication in breastfeeding
They include, in no particular order: SSRI antidepressants e.g. sertraline, citalopram, fluoxetine, paroxetine all have anti- anxiety activity. They take 4 to 6 weeks to exert full benefit. Tri-cyclic antidepressants e.g. amitriptyline, imipramine.

What are the first line antidepressants for breastfeeding moms?

Infant exposure of antidepressants through breast milk is generally low to very low. We consider that when antidepressant treatment is indicated in women with postpartum depression, they should not be advised to discontinue breastfeeding. Paroxetine and sertraline are most likely suitable first-line agents.

What is the #1 side effect of Lexapro?

Common Lexapro side effects include nausea, headache, and diarrhea. It can also cause trouble sleeping and sexual problems. Some of these side effects eventually go away as your body gets used to the medication.

Do you gain weight on Prozac vs Zoloft?

TCAs are well known to cause more weight gain than SSRIs. Of the SSRIs, fluoxetine (Prozac) and sertraline (Zoloft) had the lowest weight gain. Zoloft and Prozac also had the lowest percentage of patients with a weight gain of 7% or more over their initial body weight (4.5% for Zoloft and 8.7% for Prozac).

What is the safest natural antidepressant?

Natural remedies for depression: Are they effective?

  • St. John’s wort.
  • SAMe. This dietary supplement is a synthetic form of a chemical that occurs naturally in the body.
  • Omega-3 fatty acids. These fats are found in cold-water fish, flaxseed, flax oil, walnuts and some other foods.
  • Saffron.
  • 5-HTP.
  • DHEA.

Which SSRI is least secreted in breast milk?

Sertraline has the lowest passage of SSRI drugs into breastmilk. Citalopram also passes into breastmilk in low levels. If a breastfeeding mother has found an antidepressant previously prescribed of benefit, that may influence the choice of drug prescribed.

What is the first drug of choice for anxiety?

Antidepressants. Antidepressants, including medications in the selective serotonin reuptake inhibitor (SSRI) and serotonin and norepinephrine reuptake inhibitor (SNRI) classes, are the first line medication treatments.

Which antidepressant is most compatible with breastfeeding?

Sertraline and paroxetine (among SSRIs) and nortriptyline and imipramine (among TCAs) are the most evidence-based medications for use during breastfeeding because of similar findings across multiple laboratories, usually undetectable infant serum levels and no reports of short term adverse events.

Natasha Lunn

Tash is an IBCLC and Business Coach helping fellow IBCLCs create fun, profitable businesses that are more than just an expensive hobby. Before becoming an IBCLC and starting her private practice - The Boobala, Tash graduated as an Osteopath in 2008 and has been in Private Practice in South West Sydney. She was also a volunteer Breastfeeding Counsellor and Community Educator with the Australian Breastfeeding Association for 6 years. Through her business, Your Lactation Biz, Tash coaches and creates products to help new and seasoned IBCLCs build businesses that suit their personality and lifestyle.

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