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How does prednisone affect the baby?

Understanding the Effects of Prednisone on Babies
Prednisone, a synthetic corticosteroid, is commonly prescribed to manage a variety of conditions, including asthma, allergies, and autoimmune disorders. However, its use during pregnancy raises important questions about its potential effects on the developing fetus and newborn.
Impact on Pregnancy and Birth Defects
Research indicates that the use of prednisone during pregnancy is generally considered safe when prescribed for necessary medical conditions. According to findings, the medication is not expected to significantly increase the risk of birth defects beyond the normal background rate. However, older studies have suggested a slight association with an increased risk of cleft lip, with or without cleft palate, particularly when taken during the first trimester. This highlights the importance of careful consideration and consultation with healthcare providers when prescribing prednisone to pregnant individuals.
Effects on the Newborn
While prednisone can be beneficial for managing maternal health issues, it can also have implications for the newborn. One of the primary concerns is the potential for adrenal suppression in the baby, especially if the mother has been on high doses or prolonged therapy. This condition occurs when the baby’s adrenal glands do not produce enough hormones, which can lead to complications.
Additionally, the medication can affect the baby’s immune system. Since corticosteroids like prednisone can suppress immune responses, there is a risk that the newborn may be more susceptible to infections. This is particularly concerning in the early weeks of life when the immune system is still developing.
Breastfeeding Considerations
For mothers who are breastfeeding, prednisone is generally considered safe, as only small amounts of the drug pass into breast milk. However, it is crucial for nursing mothers to discuss their medication regimen with healthcare providers to ensure that both maternal and infant health are prioritized.
Long-term Effects on Growth and Development
There are also considerations regarding the long-term effects of prednisone on children. Prolonged use of corticosteroids in children can potentially slow growth and development. Therefore, if a mother is on prednisone during pregnancy and continues to use it while breastfeeding, monitoring the child’s growth becomes essential.
Conclusion
In summary, while prednisone can be an effective treatment for various conditions during pregnancy, its use must be carefully managed to mitigate potential risks to the baby. Healthcare providers play a crucial role in balancing the benefits of treatment against the possible adverse effects on fetal and neonatal health. Pregnant individuals should engage in open discussions with their healthcare teams to ensure the best outcomes for both themselves and their babies.

What cannot be mixed with prednisone?

People taking prednisone should also avoid alcohol, which can exacerbate certain side effects, and they may also consider cutting out coffee and sugary drinks. Prednisone may interact with NSAIDs, diabetes medicines, immunosuppressants, blood thinners, diuretics, and some antibiotics for certain people.

Does prednisone affect milk supply?

Although it is often recommended to avoid breastfeeding for 4 hours after a dose this maneuver is not necessary because prednisone milk levels are very low. Medium to large doses of corticosteroids given systemically or injected into joints or the breast have been reported to cause temporary reduction of lactation.

What is the biggest side effect of prednisone?

Prednisone’s most common side effects are increased appetite, weight gain and insomnia. The most severe side effects of prednisone are osteoporosis, increased risk of infections and high blood pressure.

How do steroids make babies feel?

Your child may become irritable and have mood swings, and even revert to earlier childhood behaviour, such as temper tantrums. While this is usually temporary, your doctor or nurse can offer advice and support.

Does prednisone make babies irritable?

One of the potential side effects of corticosteroid medicine is mood change, such as irritability, and this can lead to difficult behaviour in some children. When used short-term, it can increase blood pressure and blood sugar levels, causing some children to become hyperactive.

Does prednisone cause a cleft palate?

The overall association of corticosteroids and cleft lip and palate in the new data was 1.0 (95% CI, 0.7–1.4). There was little evidence of associations between specific corticosteroid components or timing and clefts.

Can prednisone harm an unborn baby?

Prednisolone and pregnancy
You can take prednisolone while you’re pregnant. It has occasionally been linked to problems in the first 12 weeks of pregnancy and possible effects on the baby’s growth, however, the benefits of taking it usually outweigh any risks.

What organ is affected by prednisone?

If you take oral corticosteroids for a long time, your adrenal glands may produce less of their natural steroid hormones. To give your adrenal glands time to recover this function, your provider may reduce your dose gradually.

What can prednisone do to a baby?

Prednisone may affect the way your child’s body retains fluid and removes sodium (salt). Lowering the amount of sodium in your child’s diet can lower his or her blood pressure. Mood swings. Prednisone may cause a depressed mood.

What are the side effects of steroids in early pregnancy?

Commonly reported side-effects after taking steroids are: • Flushing of the mother’s face and chest. Some glucose appearing in the mother’s urine for a day or two. Some difficulty in getting off to sleep at night for one or two days. Some reduction in the baby’s movements for about 24 hours.

Natasha Lunn

Tash is an IBCLC and Business Coach helping fellow IBCLCs create fun, profitable businesses that are more than just an expensive hobby. Before becoming an IBCLC and starting her private practice - The Boobala, Tash graduated as an Osteopath in 2008 and has been in Private Practice in South West Sydney. She was also a volunteer Breastfeeding Counsellor and Community Educator with the Australian Breastfeeding Association for 6 years. Through her business, Your Lactation Biz, Tash coaches and creates products to help new and seasoned IBCLCs build businesses that suit their personality and lifestyle.

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